Why the study?
Does therapeutic anticoagulation reduce proximal DVT or PE in adult patients with isolated calf DVT?
Population
384 adult patients with ultrasonographic detection of an isolated calf DVT, mean age 60, 57.8% men…
Comparison
Intention to administer therapeutic… vs No therapeutic anticoagulation (control)
Design
Cohort
Follow-up
180 days
Authors
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May support anticoagulation for isolated calf DVT; leaves open net benefit and requires RCTs before practice change.
Does therapeutic anticoagulation reduce proximal DVT or PE in adult patients with isolated calf DVT?
In patients with isolated calf DVT, therapeutic anticoagulation reduces the risk of proximal DVT or PE but significantly increases the risk of bleeding.
Utter et al. (2016) studied this question.
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