July 30, 2025Open Access

Association of Post-Thrombotic Changes with Disease Severity in Patients Presenting with Symptomatic Calf Vein Thrombosis

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Discussion

Prospective study highlights recanalization outcomes in patients with calf vein thrombosis, suggesting mild disease prognosis.

Most patients with calf vein thrombosis experience significant recanalization, with 99% achieving this outcome within one year.
Reflux was observed in 22% of limbs, yet did not predict progression to severe disease in the medium term.
Ultrasound examinations showed mild post-thrombotic changes, with only 17% of limbs showing edema after one year.
The majority of patients remained asymptomatic, indicating favorable clinical outcomes after calf vein DVT.

Koustas et al. (2025) studied this question.

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