What question did this study set out to answer?

To identify the physiologic changes contributing to postthrombotic syndrome after deep venous thrombosis.

An Objective Assessment of the Physiologic Changes in the Postthrombotic Syndrome

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial assesses physiologic changes in patients with postthrombotic syndrome, suggesting valvular function loss as a key factor.

To identify the physiologic changes contributing to postthrombotic syndrome after deep venous thrombosis.
Assessment of venous outflow, venous refilling time, and valvular competence in 32 patients with deep venous thrombosis.
Follow-up ranged from nine to 144 months, averaging 41 months after the initial event.
Venous refilling time was significantly lower in limbs with incompetent valves (mean 8.4 s vs 25.3 s), indicating impaired function.
49% of patients reported pain, while objective symptoms like edema (21%), pigmentation (26%), and ulceration (3%) occurred less frequently.

Lois A. Killewich (1985) studied this question.

View Full Paper

Ask AI

Bookmark

Randomized trial assesses physiologic changes in patients with postthrombotic syndrome, suggesting valvular function loss as a key factor.