Key result
Portable coagulometers provided INR results comparable to laboratory tests, with CoaguChek XS Plus showing higher concordance (ICC 0.899) than INRatio PT Monitor (ICC 0.716).
Why the study?
Do portable coagulometers provide comparable INR results to laboratory venipuncture in patients on Vitamin K antagonists?
Population
1009 patients using Vitamin K antagonists in an anticoagulation clinic, mean age 59.6 years, 51.5% male. Key…
Comparison
INR measurement via capillary puncture using… vs INR measurement via laboratory venipuncture
Design
Cohort
Authors
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May support point-of-care INR monitoring in VKA patients; leaves open need for randomized validation of device accuracy and outcomes.
Observational (n=1,009)
No
Do portable coagulometers provide comparable INR results to laboratory venipuncture in patients on Vitamin K antagonists?
Effect estimate: ICC 0.899 (CoaguChek XS Plus) and 0.716 (INRatio PT Monitor)
Portable coagulometers, particularly the CoaguChek XS Plus, provide reliable INR measurements that correlate well with laboratory venipuncture, especially for values within or below the therapeutic range.
Meneghelo et al. (2015) conducted an observational in Patients using Vitamin K antagonists (n=1,009). Portable coagulometers (CoaguChek XS Plus and INRatio PT Monitor) vs. Laboratory tests (venipuncture) was evaluated on Correlation and concordance of INR results between portable coagulometers and laboratory tests (ICC 0.899 (CoaguChek XS Plus) and 0.716 (INRatio PT Monitor)). Portable coagulometers provided INR results comparable to laboratory tests, with CoaguChek XS Plus showing higher concordance (ICC 0.899) than INRatio PT Monitor (ICC 0.716).
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