Quality of Life, Health Status, and Depression
Key result
Patients post-Fontan procedure had lower physical health status (46.5 vs 55.9, P<.001) and higher depression scores (7.3 vs 4.5, P<.004) than healthy counterparts, despite similar overall QOL.
Why the study?
Does living with a single ventricle post-Fontan procedure affect quality of life, health status, and depression in adolescents and adults compared to healthy counterparts?
Population
120 adolescents and adults, comprising 54 with single ventricle congenital heart disease who have undergone…
Comparison
Status post Fontan procedure for single… vs Age-matched healthy counterparts
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Preserved QOL in Fontan patients despite physical and depressive deficits supports adaptation; leaves open prospective studies before guiding care.
Study Design
Type
Cross-Sectional (n=120)
Structured PICO
Does living with a single ventricle post-Fontan procedure affect quality of life, health status, and depression in adolescents and adults compared to healthy counterparts?
P
Population
120 adolescents and adults, including 54 post-Fontan procedure patients and 66 age-matched healthy counterparts.
E
Exposure
Status post Fontan procedure for single ventricle congenital heart disease
C
Comparator
Age-matched healthy counterparts
O
Outcome
Quality of life, health status, and depression measured using the Satisfaction With Life Scale, Short Form Survey Version 2, and Patient Health Questionnaire Depression Modulepatient reported
Main Result
Absolute Event Rate: 46.5% vs 55.9%
p-value: p=<.001
Despite lower physical health and higher depression levels, adolescents and adults post-Fontan procedure have a quality of life comparable to healthy peers, contradicting previous assumptions.
Cite This Study
Pike et al. (2012) conducted a cross-sectional in Single ventricle congenital heart disease (n=120). Fontan procedure vs. Healthy counterparts was evaluated on Physical health status (p=<.001). Patients post-Fontan procedure had lower physical health status (46.5 vs 55.9, P<.001) and higher depression scores (7.3 vs 4.5, P<.004) than healthy counterparts, despite similar overall QOL.