Value of Multi-Parameter Combined Application of CZT-SPECT and CCTA in Risk Stratification of Short-Term Myocardial Ischemic Events in Patients with Chronic Coronary Syndromes

Figures

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  Figure 1. Flowchart of screening and follow-up procedures. CCS: chronic coronary syndromes; CZT-SPECT: cadmium–zinc–telluride single-photon emission computed tomography; CCTA: coronary computed tomography angiography; MACEs: major adverse cardiovascular events.

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  Figure 2. Kaplan–Meier survival curves for SDS and FAI in predicting MACEs. SDS: summed difference score; FAI: perivascular fat attenuation index.

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  Figure 3. Scatter plot based on the SDS and FAI. SDS: summed difference score; FAI: perivascular fat attenuation index; MACEs: major adverse cardiovascular events.

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  Figure 4. Kaplan–Meier survival curves for combined SDS and FAI stratification in predicting MACEs. Group 1: SDS ≥ 2 + FAI ≥ −78.79; Group 2: SDS < 2 + FAI ≥ −78.79; Group 3: SDS < 2 + FAI < −78.79; Group 4: SDS ≥ 2 + FAI < −78.79. SDS: summed difference score; FAI: perivascular fat attenuation index.

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  Figure 5. A typical case example. A 37-year-old male patient was admitted with intermittent precordial pain lasting six months. (a) Myocardial perfusion tomographic images (odd rows: stress images; even rows: rest images; rows 1–4: short-axis images; rows 5–6: vertical long-axis images; rows 7–8: horizontal long-axis images). (b) Myocardial perfusion polar map showing extensive reversible changes in radioactive distribution involving the left ventricular apex, part of the anterior wall, and anteroseptal wall (accounting for approximately 25% of the left ventricular wall area), along with a small area of fixed sparse radioactivity in the mid-anterior wall (accounting for approximately 5% of the left ventricular wall area). (c) QPS/QGS quantitative analysis results: SSS = 15, SRS = 4, SDS = 11. (d) AI-based quantitative analysis of the plaque in the mid-segment of the LAD, showing that the plaque is a non-calcified plaque with two high-risk plaque features: positive remodeling and low-attenuation plaque. (e) AI-automated measurement of FAI around the LAD: −87.13 HU.