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August 30, 2026Journal of Feline Medicine and SurgeryOpen Access

EXPRESS: Colonization of Helicobacter Species and Associated Gastritis in Cats with Gastrointestinal disease: a Cross-Sectional Study on 154 Cases

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Authors

TITeija Kaarina ImmonenUniversity of HelsinkiJVJenni VirtanenUniversity of HelsinkiHVHanna VauhkonenUniversity of Helsinki

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Implication

Cross-sectional study finds Helicobacter colonization linked to lymphoplasmacytic gastritis in cats with chronic gastrointestinal disease, indicating a potential role in mucosal inflammation.

Key Points

  • To evaluate the prevalence of gastric Helicobacter colonization, identify colonizing species, and investigate associations with histopathological gastritis in cats with chronic gastrointestinal disease.
  • Prospectively enrolled 154 client-owned cats with suspected chronic gastrointestinal signs that underwent full-thickness gastric and small intestinal biopsies between May 2018 and December 2022.
  • Assessed gastric histopathology and bacterial colonization via tissue biopsies, performing nanopore sequencing on a subset of samples for species-level identification.
  • Helicobacter species were detected in 75% of cats, with Helicobacter heilmannii being the most prevalent organism amid frequent multi-species colonization.
  • Gastritis was present in 58% of cats and significantly associated with Helicobacter presence, specifically lymphoplasmacytic gastritis, though colonization density did not correlate with gastritis severity.

Cite This Study

Immonen et al. (2026) studied this question.

synapsesocial.com/papers/6a93f1626c1a8fb52e79e4eahttps://doi.org/10.1177/1098612x261485559
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Also Consider

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  4. 4Prevalence, risk factors, and zoonotic potential of gastrointestinal helminths in cats: A participatory epidemiological study2026 · 1 citations
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