Key result
This review summarizes the effects of cardiac surgery and cardiopulmonary bypass on the brain, including neurological deficits, risk factors, and recent pharmacological neuroprotective trials.
This review summarizes current evidence on cerebral dysfunction after cardiac surgery, including risk factors, biomarkers, and neuroprotective strategies.
Updates clinicians on post-cardiac surgery cerebral risks; leaves open optimal pharmacological neuroprotection pending further trials.
This review focuses on the effects of cardiac surgery and cardiopulmonary bypass on the brain, with special emphasis on the results of recently conducted studies. The incidence of postoperative neurological and neuropsychological deficits and risk factors for cerebral injury are reviewed. The relationships between cerebral embolic load, release of biochemical markers of brain injury and cognitive dysfunction after cardiac surgery are also reviewed. Finally, recently gained information on the management of cardiopulmonary bypass is discussed, along with the results of recent pharmacological neuroprotective trials in patients undergoing cardiac surgery.
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Sven‐Erik Ricksten (2000) conducted a review in Cerebral dysfunction after cardiac surgery. Cardiac surgery and cardiopulmonary bypass was evaluated. This review summarizes the effects of cardiac surgery and cardiopulmonary bypass on the brain, including neurological deficits, risk factors, and recent pharmacological neuroprotective trials.
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