Key result
Higher cognitive functioning (3MS score) predicted lower mortality in heart failure (HR 0.94; 95% CI 0.89-0.98; P<0.01), whereas health literacy did not.
Why the study?
Health literacy has predicted mortality in heart failure, but the role of cognitive functioning in modifying this relationship had not been evaluated.
Observational (n=298)
Hazard Ratio: 0.94 (95% CI 0.89–0.98)
p-value: p=<0.01
Cognitive functioning is a stronger predictor of mortality than health literacy in patients with HFrEF, suggesting cognitive assessment may be important for risk stratification.
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Cognitive screening may refine HF mortality risk stratification; hypothesis-generating for targeted interventions.
Kuhn et al. (2021) conducted an observational in Heart failure with reduced ejection fraction (n=298). Cognitive functioning (3MS score) was evaluated on All-cause mortality (HR 0.94, 95% CI 0.89-0.98, p=<0.01). Higher cognitive functioning (3MS score) predicted lower mortality in heart failure (HR 0.94; 95% CI 0.89-0.98; P<0.01), whereas health literacy did not.
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