Key result
Ifenprodil tartrate inhibited both epinephrine-induced and shear-induced platelet aggregation in vitro, likely via inhibition of the platelet alpha-2 adrenoceptor.
Ifenprodil tartrate inhibits platelet aggregation in vitro primarily via antagonism of platelet alpha-2 adrenoceptors.
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Nakamura et al. (1999) studied Healthy volunteers (in vitro study) (n=6). Ifenprodil tartrate vs. Buffer (Control) was evaluated on Platelet aggregation (epinephrine-induced, brimonidine-induced, and shear-induced). Ifenprodil tartrate inhibited both epinephrine-induced and shear-induced platelet aggregation in vitro, likely via inhibition of the platelet alpha-2 adrenoceptor.
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