Key result
Significantly raised serum fibrin degradation product (F.D.P.) levels were found in all cases of diagnosed deep vein thrombosis and pulmonary embolism among 76 high-risk surgical patients.
Why the study?
Does serum F.D.P. level correlate with the diagnosis of postoperative deep vein thrombosis and pulmonary embolism in high-risk surgical patients?
Population
76 high-risk surgical patients monitored postoperatively for venous thromboembolic disease.
Comparison
Measurement of serum fibrin/fibrinogen… vs Patients without thromboembolism
Design
Cohort, Laboratory staff blinded to patient clinical progress
Follow-up
Up to two weeks postoperatively or until hospital discharge
Authors
Loading...
May aid postoperative VTE diagnosis in high-risk patients; hypothesis-generating and should not yet change practice.
Observational (n=76)
Does serum F.D.P. level correlate with the diagnosis of postoperative deep vein thrombosis and pulmonary embolism in high-risk surgical patients?
Serum F.D.P. levels are significantly elevated in postoperative pulmonary embolism and may serve as a valuable diagnostic biomarker, though they are less useful for detecting deep vein thrombosis.
Ruckley et al. (1970) conducted an observational in Venous thromboembolic disease (n=76). Serum Fibrin/Fibrinogen Degradation Products (F.D.P.) was evaluated on Episodes of deep vein thrombosis and pulmonary embolism. Significantly raised serum fibrin degradation product (F.D.P.) levels were found in all cases of diagnosed deep vein thrombosis and pulmonary embolism among 76 high-risk surgical patients.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: