Key result
A patient with severe ovarian hyperstimulation syndrome developed cortical vein thrombosis that initially mimicked an intracranial haemorrhage on MRI.
Case Report (n=1)
Thrombosis should be considered as a primary differential for intracranial lesions in patients with OHSS, even if initial MRI suggests haemorrhage.
Highlights thrombosis as possible mimic of hemorrhage in OHSS; hypothesis-generating and should not yet change practice.
A case of cortical vein thrombosis presenting as intracranial haemorrhage is described in a patient with ovarian hyperstimulation syndrome (OHSS) after IVF and embryo transfer. Veno-occlusive disease of the brain could appear as a haemorrhagic lesion on magnetic resonance imaging (MRI) and this made the initial diagnosis of cortical vein thrombosis difficult. The patient developed deep vein thrombosis 2 weeks after the intracranial event and the diagnosis of cortical vein thrombosis was made at that time on MRI study after the resolution of the haemorrhage. This patient actually developed generalized thrombosis as a complication to OHSS. Although the initial MRI picture may be misleading, the diagnosis of thrombosis should always be kept in mind, as it is the commonest cause of intracranial lesions after OHSS.
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Tang et al. (2000) conducted a case report in Ovarian hyperstimulation syndrome (OHSS) (n=1). Ovarian hyperstimulation syndrome (OHSS) was evaluated on Cortical vein thrombosis. A patient with severe ovarian hyperstimulation syndrome developed cortical vein thrombosis that initially mimicked an intracranial haemorrhage on MRI.
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