Key result
LMWH successfully resolves gonadotrophin-induced internal jugular vein thrombosis without underlying OHSS.
Why the study?
Thromboembolic events following ovarian stimulation for IVF are serious but rare, with unclear risk factors in some cases.
Case Report (n=1)
Internal jugular vein thrombosis can occur as a rare complication of ovarian stimulation even without OHSS or hereditary hypercoagulability, and can be successfully treated with low molecular weight heparin.
Answers are grounded in this paper and cite their sources.
Thrombosis can occur after ovarian stimulation without OHSS or thrombophilia; case report leaves open need for targeted prophylaxis studies.
Thromboembolic events are serious, but fortunately rare, complications following ovarian stimulation for IVF. Here, we report a case of internal jugular vein thrombosis after ovarian stimulation with gonadotrophins. Most of the cases of thrombosis are late complications of ovarian hyperstimulation syndrome (OHSS) or hereditary hypercoagulability. Screening for these risk factors in our patient was negative. The patient was successfully treated with low molecular weight heparin and a twin pregnancy is ongoing.
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Belaen et al. (2001) conducted a case report in Internal jugular vein thrombosis (n=1). Ovarian stimulation with gonadotrophins was evaluated on Internal jugular vein thrombosis. A patient developed internal jugular vein thrombosis after ovarian stimulation with gonadotrophins despite negative screening for OHSS and hypercoagulability, and was successfully treated with LMWH.
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