What is the clinical evidence from this study?

Study design: Case Report. Population: Deep vein thrombosis and internal jugular vein thrombosis (n=1). Intervention: In vitro fertilization. Primary outcome: Deep vein thrombosis and internal jugular vein thrombosis.

July 18, 2003American Journal of HematologyOpen Access

Deep vein thrombosis followed by internal jugular vein thrombosis as a complication of in vitro fertilization in a woman heterozygous for the prothrombin 3′ UTR and factor V Leiden mutations

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Key result

IVF linked to DVT and jugular vein thrombosis in a woman with inherited thrombophilia.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 30-year-old woman heterozygous for prothrombin 3' UTR and factor V Leiden mutations who developed proximal deep vein thrombosis and subsequent internal jugular vein thrombosis following in vitro fertilization.

Exposure

In vitro fertilization

Outcome

Proximal deep vein thrombosis and subsequent internal jugular vein thrombosis extending into the subclavian and axillary veinsafety

Thromboembolic events such as internal jugular vein thrombosis can occur after in vitro fertilization in patients with underlying prothrombotic abnormalities, emphasizing the importance of thrombophilia screening in high-risk women.

Authors

BMBarbara McGowanKing's College London LKLaurence KayInserm DPDavid J. PerryUniversity of Liverpool

Discussion

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Implication

Highlights possible post-IVF thrombosis in thrombophilia; hypothesis-generating and should not yet alter screening practice.

Cite This Study

McGowan et al. (2003) conducted a case report in Deep vein thrombosis and internal jugular vein thrombosis (n=1). In vitro fertilization was evaluated on Deep vein thrombosis and internal jugular vein thrombosis. A 30-year-old woman with prothrombin and factor V Leiden mutations developed deep vein thrombosis and subsequent internal jugular vein thrombosis following in vitro fertilization.

synapsesocial.com/papers/6aa4db08549833fcd32bc44f https://doi.org/10.1002/ajh.10367

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Deep vein thrombosis followed by internal jugular vein thrombosis as a complication of in vitro fertilization in a woman heterozygous for the prothrombin 3′ UTR and factor V Leiden mutations

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Deep vein thrombosis followed by internal jugular vein thrombosis as a complication of in vitro fertilization in a woman heterozygous for the prothrombin 3′ UTR and factor V Leiden mutations

Study Design

Structured PICO

Discussion

Implication

Cite This Study

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