Key result
A pregnant woman with combined heterozygous factor V Leiden and prothrombin G20210A mutations and prior DVT was successfully treated with nadroparin, delivering a healthy baby without complications.
Case Report (n=1)
In a pregnant woman with combined heterozygous factor V Leiden and prothrombin G20210A mutations and prior DVT, treatment with low-molecular weight heparin resulted in a successful pregnancy without thromboembolic complications.
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May support nadroparin in combined thrombophilia pregnancies; hypothesis-generating case leaves open need for controlled data.
Couto et al. (2005) conducted a case report in Pregnancy-associated venous thromboembolism with combined heterozygous factor V Leiden and prothrombin G20210A mutations (n=1). Low-molecular weight heparin (nadroparin) was evaluated on Obstetric morbidity and thromboembolic complications. A pregnant woman with combined heterozygous factor V Leiden and prothrombin G20210A mutations and prior DVT was successfully treated with nadroparin, delivering a healthy baby without complications.
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