The Serum Proteins in Rheumatoid Arthritis

Article1 January 1950THE SERUM PROTEINS IN RHEUMATOID ARTHRITISALLAN D. WALLIS, M.D.ALLAN D. WALLIS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-1-63 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOne of the unexplained aspects of rheumatoid (atrophic) arthritis is its effect on the proteins of the blood. Using sulfate fractionation, Davis1 found that severe rheumatoid arthritis is regularly accompanied by a decrease in the plasma albumin and an increase in the plasma globulin, particularly the euglobulin fraction. The albumin-globulin (A-G) ratio was correspondingly lowered, as follows:normal range 1.81-2.35 (average 2.12)rheumatoid arthritis:severe 0.69-1.07 (average 0.90)moderate 1.11-1.83 (average 1.47)"arrested" 1.24-1.95 (average 1.52)Significant changes were not found in the total protein. 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PETERSDORF, M.D.Aetiology and pathogenesis of rheumatoid arthritisFILTER PAPER ELECTROPHORESIS OF SERUM PROTEINS IN CLINICAL PRACTICERHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., EDWARD W. BOLAND, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., WALLACE GRAHAM, M.D., F.R.C.P. (C), L. MAXWELL LOCKIE, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D.Weitere Untesuchungen �ber die Dysprotein�mie beim Rheumatismus verus und verwandten KrankheitenDie Elektrophorese bei inneren KrankheitenDie Elektrophorese in der PädiatrieThe serum proteins in rheumatic diseasesPlasma and Serum Proteins in Chronic Rheumatic DiseasesA Theory of the Pathogenesis of Rheumatoid ArthritisSOME OBSERVATIONS ON THE EOSINOPHILH. J. L. M. 1 January 1950Volume 32, Issue 1Page: 63-71KeywordsBloodBlood plasmaChemical analysisChemical fractionationGlobulinsProteinsRheumatoid arthritisSerum proteinsSulfatesSurgery ePublished: 1 December 2008 Issue Published: 1 January 1950 PDF downloadLoading ...