January 1, 1998Journal of Cardiovascular Pharmacology
Diabetic Hypertensive Patients: Improving Their Prognosis
Key result
Reducing blood pressure to <130/85 mm Hg, particularly with ACE inhibitors or nondihydropyridine calcium-channel blockers, retards the progression of renal disease in diabetic patients.
Why the study?
Do antihypertensive medications and aggressive blood pressure control improve renal prognosis in hypertensive diabetic patients?
Population
Hypertensive diabetic patients
Design
Review
Authors
Discussion
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Member takes
Implication
Supports renal preservation strategies in diabetic hypertension; leaves open optimal targets and agents in modern RCTs.
Structured PICO
Do antihypertensive medications and aggressive blood pressure control improve renal prognosis in hypertensive diabetic patients?
P
Population
Hypertensive diabetic patients
I
Intervention
Antihypertensive medications (including ACE inhibitors and nondihydropyridine calcium-channel blockers) and blood pressure reduction to <130/85 mm Hg
O
Outcome
Preservation of renal function and prevention of end-stage renal disease
Aggressive blood pressure control (<130/85 mm Hg) using agents like ACE inhibitors is crucial for preserving renal function in diabetic hypertensive patients.
Cite This Study
Makrilakis et al. (1998) conducted a review in Diabetic hypertension. Antihypertensive medications and blood pressure reduction was evaluated. Reducing blood pressure to <130/85 mm Hg, particularly with ACE inhibitors or nondihydropyridine calcium-channel blockers, retards the progression of renal disease in diabetic patients.