Key result
Pharmacological block of autonomic effectors revealed that the rise in resting iliac bed vascular resistance in renal hypertensive rabbits was entirely accounted for by an increase in the non-autonomic component.
Population
Unanaesthetized renal hypertensive and normotensive rabbits with previously implanted Doppler flowmeters
Comparison
Pharmacological block of autonomic effectors and… vs Normotensive rabbits and baseline measurements…
Design
Preclinical
Authors
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Non-autonomic factors drive vascular resistance in this model; leaves open relevance to human hypertension.
The rise in resting iliac bed vascular resistance in renal hypertensive rabbits is entirely accounted for by the non-autonomic component, which is partly due to structural changes.
West et al. (1975) studied Renal hypertension. Pharmacological block of autonomic effectors vs. Before block / normotensive rabbits was evaluated on Iliac bed vascular resistance (IVR) components. Pharmacological block of autonomic effectors revealed that the rise in resting iliac bed vascular resistance in renal hypertensive rabbits was entirely accounted for by an increase in the non-autonomic component.
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