Population
Conscious dogs
Comparison
Intravenous infusion of angiotensin II… vs Control levels of perfusion pressure
Design
Preclinical
Authors
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Differential autoregulation may shape regional TPR contributions in hypertension models; leaves open translation to human physiology and practice.
Under conditions of increased systemic blood pressure, renal and mesenteric vascular beds contribute to increased total peripheral resistance via pressure-dependent vasoconstriction, whereas the hindlimb does not.
Hellebrekers et al. (1990) studied this question.
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