Population
7 conscious dogs instrumented for measurement of aortic pressure, central venous pressure, and cardiac…
Comparison
Intravenous administration of pressor agents… vs Constant infusion of the same pressor agents…
Design
Preclinical
Follow-up
acute (15-min periods)
Authors
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Autoregulatory amplification of vasoconstriction varies by agent in animals; leaves open relevance to human MAP regulation.
The direct vasoconstrictor effects of pressor agents are significantly amplified by secondary autoregulatory responses.
Metting et al. (1989) studied this question.
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