Key result
Patients with intradialytic hypotension exhibited significantly higher pre-dialysis total power (650.30 ms2) compared to patients with increased (94.94 ms2) or stable (108.11 ms2) blood pressure (p=0.02).
Why the study?
Intradialytic hypotension increases cardiovascular morbidity and mortality in chronic hemodialysis patients, and cardiac autonomous neuropathy might be involved.
Does cardiac autonomic control differ between hemodialysis patients with and without intradialytic hypotension?
Cross-Sectional (n=52)
No
Does cardiac autonomic control differ between hemodialysis patients with and without intradialytic hypotension?
Absolute Event Rate: 650.3% vs 108.11%
p-value: p=0.02
Contrary to previous studies, Senegalese hemodialysis patients with intradialytic hypotension exhibited better pre-dialysis heart rate variability and less severe cardiac autonomic neuropathy than those without, suggesting other mechanisms drive the condition in this population.
May support CAN screening in hemodialysis; leaves open whether neuropathy predicts IDH.
Background: Intradialytic hypotension (IDH) increases cardiovascular morbidity and mortality in chronic hemodialysis patients and cardiac autonomous neuropathy (CAN) might be involved. To assess cardiac autonomic control in hemodialysis patients and describe its relationship with IDH. Methods: We conducted a prospective study at Ouakam Military Hospital in Senegal from January 1st to March 31st, 2023. Fifty-two patients (31 men, mean age 47.54 years) were included and had 3 measurements of heart rate variability (HRV): before, during and after an index hemodialysis session. They were classified according to changes in systolic blood pressure (SBP) during hemodialysis into three groups: 14 patients in group I (increase > 10 mmHg in mean intradialytic SBP), 13 in group II (decrease ≥ 20 mmHg in mean intradialytic SBP or MAP > 10 mmHg) and 25 in group III (others). HRV frequency domain indices between groups were compared. Results: , p = 0.01) compared to those in groups I and III. Also, they presented less severe CAN (16.2% vs. 57.2% and 56%, p = 0.03). Measures after dialysis found no difference in HRV parameters among the three groups. Conclusion: Our results found that HRV was similar between patients with and without IDH suggesting the influence of other risk factors that need to be explored in further studies.
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Sarr et al. (2025) conducted a cross-sectional in Chronic hemodialysis (n=52). Intradialytic hypotension vs. No intradialytic hypotension was evaluated on Pre-dialysis Total Power (TP) heart rate variability (p=0.02). Patients with intradialytic hypotension exhibited significantly higher pre-dialysis total power (650.30 ms2) compared to patients with increased (94.94 ms2) or stable (108.11 ms2) blood pressure (p=0.02).
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