Key result
Nitrate therapy for angina commonly causes headaches in up to 82% of patients, with nearly 10% unable to tolerate treatment due to disabling headaches or dizziness.
Why the study?
What are the side effects associated with using nitrates to treat angina?
Population
Patients with angina
Design
Review
Authors
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Nitrates' high headache burden warrants proactive monitoring and dose titration in angina; leaves open better-tolerated alternatives.
What are the side effects associated with using nitrates to treat angina?
While nitrates are effective for angina, they carry significant side effects, including frequent headaches and potentially serious adverse events like hypotension and increased mortality with continuous use, necessitating careful patient management.
Thadani et al. (2006) conducted a review in angina. Nitrates was evaluated. Nitrate therapy for angina commonly causes headaches in up to 82% of patients, with nearly 10% unable to tolerate treatment due to disabling headaches or dizziness.
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