Key result
125I-labelled fibrinogen uptake and venography agreed on thrombus presence in 72% of cases, but the fibrinogen test significantly underestimated the extent of femoral vein thrombosis (p<0.001).
Why the study?
How does 125I-labelled fibrinogen uptake compare to venography in the detection of recent deep-vein thrombosis in the legs?
Population
72 legs examined for recent deep-vein thrombosis
Comparison
125I-labelled fibrinogen uptake test vs Venography
Design
Cross-sectional
Authors
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Fibrinogen uptake may underestimate femoral DVT extent; leaves open its adjunctive diagnostic role versus venography.
Observational (n=72)
How does 125I-labelled fibrinogen uptake compare to venography in the detection of recent deep-vein thrombosis in the legs?
p-value: p=<0.001
While 125I-labelled fibrinogen uptake and venography agree in the majority of cases for detecting DVT, the fibrinogen test significantly underestimates the extent of femoral vein thrombosis.
McIvor et al. (1975) conducted an observational in Deep-vein thrombosis (n=72). 125I-labelled fibrinogen uptake vs. Venography was evaluated on Agreement about the presence or absence of thrombus (p=<0.001). 125I-labelled fibrinogen uptake and venography agreed on thrombus presence in 72% of cases, but the fibrinogen test significantly underestimated the extent of femoral vein thrombosis (p<0.001).
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