Key result
An alternative treatment was not significantly better than warfarin sodium for preventing venous thrombosis, and subcutaneous heparin was associated with problematic wound hematomas.
Why the study?
Does the 125I-fibrinogen leg scan accurately detect venous thrombosis, and is subcutaneous heparin better than warfarin for prevention in patients undergoing hip replacement surgery?
Population
157 patients who underwent hip replacement surgery
Comparison
125I-fibrinogen leg scan technique; subcutaneous… vs Phlebograms; warfarin sodium
Design
Other
Authors
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May warrant caution with subcutaneous heparin after hip replacement; leaves open optimal venous thrombosis prophylaxis.
RCT (n=157)
Does the 125I-fibrinogen leg scan accurately detect venous thrombosis, and is subcutaneous heparin better than warfarin for prevention in patients undergoing hip replacement surgery?
The 125I-fibrinogen leg scan is a sensitive method for detecting venous thrombosis after hip surgery, while subcutaneous heparin prophylaxis is limited by wound hematomas compared to warfarin.
Michael Hume (1973) conducted an RCT in Venous thrombosis (n=157). Alternative treatment (including subcutaneous heparin sodium) vs. Warfarin sodium was evaluated on Venous thrombosis. An alternative treatment was not significantly better than warfarin sodium for preventing venous thrombosis, and subcutaneous heparin was associated with problematic wound hematomas.
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