Why the study?
Does (125)I-fibrinogen improve the detection of venous thrombosis compared to clinical assessment in high-risk surgical patients?
Population
111 surgical patients at high risk of venous thrombosis
Comparison
(125)I-fibrinogen to detect venous thrombosis vs Independent clinical assessment
Design
Cohort, independent clinical assessment
Follow-up
postoperative period
Authors
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Clinical assessment misses most postoperative venous thromboses; leaves open whether routine objective screening improves outcomes in high-risk surgical patients.
Does (125)I-fibrinogen improve the detection of venous thrombosis compared to clinical assessment in high-risk surgical patients?
Clinical assessment is highly inaccurate for diagnosing postoperative venous thrombosis, highlighting the need for objective diagnostic methods like (125)I-fibrinogen and widespread prophylaxis.
Lambie et al. (1970) studied this question.
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