Key result
Cold Ringer's acetate infusion increased mean arterial pressure from 82 to 96 mmHg with a fall in heart rate, whereas warm infusion produced no changes in blood pressure or heart rate.
Why the study?
Does cold Ringer's acetate infusion alter haemodynamic parameters and fluid balance compared to warm infusion in healthy volunteers?
Does cold Ringer's acetate infusion alter haemodynamic parameters and fluid balance compared to warm infusion in healthy volunteers?
Cold Ringer's acetate infusion increases mean arterial pressure and decreases heart rate compared to warm infusion, despite both inducing similar haemodilution.
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May raise MAP in healthy volunteers; hypothesis-generating for fluid temperature effects in patients.
Tølløfsrud et al. (1993) studied healthy volunteers (n=20). Cold Ringer's acetate infusion (18 degrees C) vs. Warm Ringer's acetate infusion (36 degrees C) was evaluated on mean arterial pressure. Cold Ringer's acetate infusion increased mean arterial pressure from 82 to 96 mmHg with a fall in heart rate, whereas warm infusion produced no changes in blood pressure or heart rate.