Key result
Among individuals with cardiovascular risk factors and borderline ankle-brachial index, endothelial dysfunction was present in 23% of subjects, with lower reactive hyperemia index in those with impaired fasting glucose (P=0.02).
Population
66 individuals with cardiovascular risk and borderline ABI. Excluded: previously diagnosed diabetes or…
Design
Cross-sectional
Authors
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May identify high-risk patients with borderline ABI and impaired fasting glucose; leaves open whether endothelial testing refines risk stratification.
Cross-Sectional (n=66)
Nearly one-quarter of patients with cardiovascular risk factors and borderline ABI have endothelial dysfunction, suggesting a need for aggressive risk factor management.
Syvänen et al. (2011) conducted a cross-sectional in Cardiovascular risk with borderline ankle-brachial index (n=66). Borderline ankle-brachial index was evaluated on Endothelial dysfunction (reactive hyperemia index < 1.67). Among individuals with cardiovascular risk factors and borderline ankle-brachial index, endothelial dysfunction was present in 23% of subjects, with lower reactive hyperemia index in those with impaired fasting glucose (P=0.02).
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