Key result
Among Chinese individuals, hypertension was associated with significantly lower scores for physical components of health-related quality of life (MD -4.93; 95% CI -8.40 to -1.47).
Why the study?
Does hypertension reduce health-related quality of life in the Chinese population?
Meta-Analysis
Does hypertension reduce health-related quality of life in the Chinese population?
Mean Difference: -4.93 (95% CI -8.4–-1.47)
Hypertension is associated with worse health-related quality of life, specifically in physical components, among the Chinese population.
Confirms lower HRQOL with hypertension in Chinese adults; leaves open causal effects and intervention benefits.
AIMS: Many observational studies have shown a lower health-related quality of life (HRQOL) of hypertension patients. This study aimed to summarize the association between hypertension and HRQOL in the Chinese population. METHODS: We systematically searched the observational studies in the following databases: Medline, PubMed, Embase, Science Citation Index, Chinese National Knowledge Infrastructure, VIP and WanFang Data from 1 January 1990 to 1 October 2017. RESULTS: A total of 33 studies were included in this systematic review. Twenty-one of them presented worse quality of life in hypertensive individuals. The meta-analysis showed lower scores in hypertensive individuals for the eight domains and physical components (-4.93; 95% confidence interval -8.40 to -1.47), and no statistical difference in mental components (-1.62; 95% confidence interval -4.26 to 1.02). CONCLUSION: Among Chinese patients, HRQOL of hypertensive patients is worse than that of normotensive individuals. These data suggest that maintenance of normotension offers benefits on patient-centered outcomes, in addition to other well established cardiovascular benefits.
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Ye et al. (2018) conducted a meta-analysis in Hypertension. Hypertension vs. Normotension was evaluated on Physical components of health-related quality of life (MD -4.93, 95% CI -8.40 to -1.47). Among Chinese individuals, hypertension was associated with significantly lower scores for physical components of health-related quality of life (MD -4.93; 95% CI -8.40 to -1.47).
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