Key result
Plasma renin and erythropoietin were elevated in 37% and 63% of patients with renal adenocarcinoma respectively, with renin predicting a poor prognosis and high-grade lesions.
Why the study?
Are plasma renin, erythropoietin, and chorionic gonadotropin levels useful as biochemical tumor markers in patients with renal adenocarcinoma?
Population
57 patients with renal adenocarcinoma
Design
Cohort
Authors
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May support renin and erythropoietin as markers in renal adenocarcinoma; leaves open prospective validation before clinical use.
Observational (n=57)
Are plasma renin, erythropoietin, and chorionic gonadotropin levels useful as biochemical tumor markers in patients with renal adenocarcinoma?
Renin and erythropoietin determinations may be valuable as biochemical tumor markers in renal adenocarcinoma, with renin elevation predicting a poor prognosis.
Sufrin et al. (1977) conducted an observational in Renal adenocarcinoma (n=57). Plasma renin, erythropoietin, and chorionic gonadotropin levels was evaluated on Hormone elevation and correlation with tumor characteristics and prognosis. Plasma renin and erythropoietin were elevated in 37% and 63% of patients with renal adenocarcinoma respectively, with renin predicting a poor prognosis and high-grade lesions.
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