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April 3, 2002Journal of Medical Virology

Epidemiology of human sapporo‐like caliciviruses in the South West of England: Molecular characterisation of a genetically distinct isolate*

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Key result

Sequence analysis of 18 Sapporo-like virus isolates from gastroenteritis samples indicated they belong to two major genetic groups, with the Bristol/98 isolate fully sequenced and characterized.

Population

27 clinical samples containing Sapporo-like viruses collected during a 3-year surveillance of…

Design

Other

Authors

SRSamantha RobinsonMcGill University Health CentreICIan N. ClarkeSouthampton General HospitalIVIan B. VipondUniversity of Liverpool

Discussion

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Implication

Supports reclassification of Sapporo-like viruses into two groups; leaves open effects on diagnostics or surveillance pending validation.

Study Design

Type

Observational (n=27)

Structured PICO

P
Population
27 clinical samples containing Sapporo-like viruses collected during a 3-year surveillance of gastroenteritis in the South West of England.
E
Exposure
Molecular characterization including PCR amplification and full genome sequence analysis
O
Outcome
Genetic grouping and full genomic sequence analysis of the isolates

Phylogenetic analysis of complete capsid sequences and genome arrangements indicates that human enteric viruses within the Sapporo-like virus clade should be divided into two distinct genetic groups.

Cite This Study

Robinson et al. (2002) conducted an observational in Gastroenteritis (n=27). Sapporo-like caliciviruses (SLVs) was evaluated on Molecular characterization and phylogenetic analysis of SLV isolates. Sequence analysis of 18 Sapporo-like virus isolates from gastroenteritis samples indicated they belong to two major genetic groups, with the Bristol/98 isolate fully sequenced and characterized.

synapsesocial.com/papers/6a940f649fbe5f86ceb95211https://doi.org/10.1002/jmv.2219
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Also Consider

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