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November 1, 1994Journal of Medical Virology

Genomic diversity of small round structured viruses in the United Kingdom

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Population

52 faecal specimens collected in the United Kingdom between 1986 and 1992 containing small round structured…

Design

Other

Authors

JNJ P NorcottUniversity of CambridgeJGJ. GreenCentral Middlesex HospitalDLD. C. LewisUniversity of Bristol

Discussion

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Overview

Three SRSV genomic groups identified in UK specimens; extends molecular epidemiology but leaves open clinical and antigenic correlations.

Structured PICO

P
Population
52 faecal specimens collected in the United Kingdom between 1986 and 1992 containing small round structured virus (SRSV) particles
I
Intervention
Reverse transcriptase polymerase chain reaction (RT-PCR) assays using two primer pairs (SM51/31 and SM52/32) and sequencing of a 266 bp region of the RNA polymerase gene
O
Outcome
Genomic variation and phylogenic grouping

Phylogenic analysis of SRSV strains in the UK identified three distinct genomic groups with varying correlation to antigen typing.

Cite This Study

Norcott et al. (1994) studied this question.

synapsesocial.com/papers/6a70099d78a11c550e09d481https://doi.org/10.1002/jmv.1890440312
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sequence diversity of small, round-structured viruses in the Norwalk virus group1994 · 244 citations
  2. 2Norwalk-like viruses: demonstration of genomic diversity by polymerase chain reaction1993 · 117 citations
  3. 3Visualization by Immune Electron Microscopy of a 27-nm Particle Associated with Acute Infectious Nonbacterial Gastroenteritis1972 · 1,134 citations
  4. 4Attempts to serologically classify feline caliciviruses on a national and an international basis1976 · 26 citations
  5. 5Sequence and Genome Organization of a Human Small Round-Structured (Norwalk-Like) Virus1993 · 380 citations