Key result
In healthy Korean adults, serum IGF-1 levels decreased with age, showing the strongest negative correlation with age among all measured factors.
Cross-Sectional (n=10,681)
No
In healthy Korean adults, serum IGF-1 levels decrease significantly with age, establishing age as the strongest correlating factor for IGF-1 concentrations.
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Age dominates IGF-1 decline in healthy Korean adults; leaves open whether levels predict or modify cardiometabolic outcomes.
The concern about growth hormone, used for treatment of growth hormone deficiency, wasting diseases, is increasing recently. There is much to be desired about the study for the reference range of insulin-like growth factor-1 (IGF-1) of Korean healthy adults, because there was a lack of studies of IGF-1 level. The authors investigated the concentration of IGF-1 according to age groups, and its correlation factors in healthy adults in Korea.
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Choi et al. (2009) conducted a cross-sectional in Healthy adults (n=10,681). Age was evaluated on Correlation between age and serum IGF-1 level (R: -0.325 for men, R: -0.463 for women, p=<0.001). In healthy Korean adults, serum IGF-1 levels decreased with age, showing the strongest negative correlation with age among all measured factors.
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