Key result
The E3+GHBP and E3-GHBP isoforms do not correlate with each other (r = 0.67), and their relative proportion is gender-dependent with a higher E3-GHBP proportion in females (P < 0.01).
Population
141 subjects with average weight, overweight and obesity
Design
Cross-sectional
Authors
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GHBP isoforms show gender-specific proportions without correlation; leaves open distinct metabolic associations in observational data.
Cross-Sectional (n=141)
Effect estimate: r = 0.67
p-value: p=< 0.01
The exon 3-retaining and exon 3-deleted isoforms of GHBP are regulated differently and have distinct correlations with adiposity and metabolic risk factors.
Kratzsch et al. (2001) conducted a cross-sectional in Average weight, overweight, and obesity (n=141). E3+GHBP and E3-GHBP isoforms was evaluated on Correlation between E3+GHBP and E3-GHBP isoforms and gender dependence (r = 0.67, p=< 0.01). The E3+GHBP and E3-GHBP isoforms do not correlate with each other (r = 0.67), and their relative proportion is gender-dependent with a higher E3-GHBP proportion in females (P < 0.01).
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