Key result
Every 1 m/s increase in estimated pulse wave velocity was associated with a 56% increased risk of all-cause mortality in adults with diabetes (HR 1.56; 95% CI, 1.44 to 1.69).
Why the study?
Whether arterial stiffness estimated by ePWV predicts all-cause and cause-specific mortality in patients with diabetes mellitus had not been reported.
Is estimated pulse wave velocity (ePWV) associated with all-cause and cause-specific mortality in adults with diabetes mellitus?
Population
5,235 U.S. adults with DM (age >=20 years)
Comparison
Arterial stiffness estimated by ePWV
Design
Prospective cohort study
Follow-up
Median 115 months
Authors
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May enhance mortality risk stratification in diabetes; extends observational data but leaves causal role open.
Cohort (n=5,235)
Yes
Is estimated pulse wave velocity (ePWV) associated with all-cause and cause-specific mortality in adults with diabetes mellitus?
Hazard Ratio: 1.56 (95% CI 1.44–1.69)
Estimated pulse wave velocity is a strong, independent predictor of all-cause and cause-specific mortality in patients with diabetes mellitus.
Liu et al. (2023) conducted a cohort in diabetes mellitus (n=5,235). Estimated pulse wave velocity (ePWV) was evaluated on all-cause mortality (HR 1.56, 95% CI 1.44 to 1.69). Every 1 m/s increase in estimated pulse wave velocity was associated with a 56% increased risk of all-cause mortality in adults with diabetes (HR 1.56; 95% CI, 1.44 to 1.69).
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