Key result
Elevated mean platelet volume was significantly associated with increased arterial stiffness as measured by brachial-ankle pulse wave velocity (β = 0.198; P < 0.001).
Why the study?
Is mean platelet volume associated with arterial stiffness (measured by baPWV) in apparently healthy individuals?
Population
2645 apparently healthy Chinese participants (1676 men, 969 women) undergoing a general health examination
Comparison
Mean platelet volume assessment vs Comparison across MPV quintiles
Design
Cross-sectional
Authors
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May indicate platelet involvement in early vascular changes; leaves open predictive value for events in healthy populations.
Cross-Sectional (n=2,645)
Is mean platelet volume associated with arterial stiffness (measured by baPWV) in apparently healthy individuals?
Effect estimate: β = 0.198
p-value: p=<0.001
Elevated mean platelet volume is positively correlated with arterial stiffness in apparently healthy individuals.
Wang et al. (2011) conducted a cross-sectional in Apparently healthy (n=2,645). Mean platelet volume (MPV) vs. Lower MPV was evaluated on Brachial-ankle pulse wave velocity (baPWV) (β = 0.198, p=<0.001). Elevated mean platelet volume was significantly associated with increased arterial stiffness as measured by brachial-ankle pulse wave velocity (β = 0.198; P < 0.001).
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