Key result
Outpatient treatment of acute pulmonary embolism with direct oral anticoagulants resulted in 0% recurrent VTE, 0.4% major bleeding, and 0.4% mortality over 6 months of follow-up.
Why the study?
Does outpatient treatment with direct oral anticoagulants prevent recurrent VTE and bleeding in selected patients with acute pulmonary embolism?
Population
245 patients in the southernmost hospital region in Sweden treated with direct oral anticoagulants for acute…
Design
Cohort
Follow-up
6 months
Authors
Loading...
May support outpatient DOAC use in selected low-risk PE; leaves open need for RCTs before practice change.
Cohort (n=245)
Yes
Does outpatient treatment with direct oral anticoagulants prevent recurrent VTE and bleeding in selected patients with acute pulmonary embolism?
Outpatient treatment of acute pulmonary embolism with direct oral anticoagulants is effective and safe in selected low-risk patients, with no VTE recurrences and very low bleeding rates at 6 months.
Ghazvinian et al. (2018) conducted a cohort in Pulmonary embolism (n=245). Outpatient treatment with direct oral anticoagulants (DOAC) was evaluated on Recurrent venous thromboembolism (VTE) at 6 months. Outpatient treatment of acute pulmonary embolism with direct oral anticoagulants resulted in 0% recurrent VTE, 0.4% major bleeding, and 0.4% mortality over 6 months of follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: