Why the study?
Intestinal barrier dysfunction plays a critical role in perioperative complications, particularly when the immunologic barrier is damaged.
Design
Review
Key result
Intestinal immunologic barrier dysfunction increases the risk of perioperative complications, including infection, anastomotic leakage, gastrointestinal motility disorders, and systemic inflammatory response syndrome.
Authors
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May warrant gut barrier monitoring in high-risk surgery; leaves open targeted interventions pending trials.
Intestinal immunologic barrier dysfunction during the perioperative period significantly increases the risk of complications, emphasizing the need for interventions targeting intestinal homeostasis.
Hu et al. (2025) conducted a review in Perioperative complications. Intestinal immunologic barrier dysfunction was evaluated. Intestinal immunologic barrier dysfunction increases the risk of perioperative complications, including infection, anastomotic leakage, gastrointestinal motility disorders, and systemic inflammatory response syndrome.