Key result
A 17-year-old male presenting with pericarditis was diagnosed with Graves thyrotoxicosis and improved following treatment with anti-inflammatory and antithyroid agents.
Case Report (n=1)
Pericarditis can be a rare initial presentation of Graves disease in pediatric patients, requiring recognition and treatment with anti-inflammatory and antithyroid agents.
Clinicians should consider Graves disease in unexplained pediatric pericarditis; single case leaves open need for routine thyroid evaluation.
Pericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis. The patient was treated with anti-inflammatory and antithyroid agents and improved in time. We discuss previously reported cases of Graves disease-associated pericarditis in adults, potential etiologies, and management strategies.
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Cullen et al. (2015) conducted a case report in Graves disease and pericarditis (n=1). Anti-inflammatory and antithyroid agents was evaluated on Clinical improvement. A 17-year-old male presenting with pericarditis was diagnosed with Graves thyrotoxicosis and improved following treatment with anti-inflammatory and antithyroid agents.
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