Key result
NT-proBNP concentrations accurately discriminated dogs with respiratory disease from those with cardiac disease, with an optimum cut-off of 210 pmol/l.
Why the study?
Does NT-proBNP measurement accurately discriminate between cardiac and respiratory disease in dogs?
Population
77 dogs with either cardiac or respiratory disease
Design
Preclinical, Laboratory blinded to the clinical status of the patient
Authors
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May aid differentiation of cardiac from respiratory disease in dogs; leaves open prospective validation before clinical adoption.
Observational (n=77)
Single-blind
Does NT-proBNP measurement accurately discriminate between cardiac and respiratory disease in dogs?
Canine NT-proBNP is a useful marker for identifying cardiac disease, though concentrations are influenced by renal function.
Boswood et al. (2007) conducted an observational in Canine cardiac disease (n=77). NT-proBNP testing was evaluated on Discrimination of cardiac from respiratory disease. NT-proBNP concentrations accurately discriminated dogs with respiratory disease from those with cardiac disease, with an optimum cut-off of 210 pmol/l.
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