Key result
Simultaneous application of viral culture and real-time reverse-transcription PCR can detect abortive respiratory syncytial virus replication in a cotton rat model.
Population
Cotton rat model of respiratory syncytial virus (RSV) infection
Design
Preclinical
Authors
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May advance RSV model research; leaves open translation to human disease.
Simultaneous application of viral culture and qRT-PCR in a cotton rat model can reveal important features of viral biology, such as abortive RSV replication.
Boukhvalova et al. (2010) studied Respiratory syncytial virus (RSV) infection. Viral culture and real-time reverse-transcription PCR (qRT-PCR) was evaluated on Detection of abortive RSV replication. Simultaneous application of viral culture and real-time reverse-transcription PCR can detect abortive respiratory syncytial virus replication in a cotton rat model.
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