Key result
In patients unfit for surgery, the 3-year risk of rupture was 41% for AAAs ≥6.0 cm compared to 28% for 5.0-5.9 cm AAAs, though the majority of patients died from other causes.
Why the study?
What is the risk of rupture and overall survival in patients with a large abdominal aortic aneurysm who are considered unfit for surgery?
Population
57 patients with an intact abdominal aortic aneurysm of 5 cm or greater in diameter considered unfit for…
Design
Cohort
Follow-up
minimum of 2 years
Authors
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High rupture risk offset by competing mortality in unfit patients with large AAAs; should not yet change practice and leaves open selective repair trials.
Cohort (n=192)
What is the risk of rupture and overall survival in patients with a large abdominal aortic aneurysm who are considered unfit for surgery?
Absolute Event Rate: 41% vs 28%
Although the risk of rupture for large AAAs in patients unfit for surgery is substantial, the majority die from other causes, suggesting that only a minority would actually benefit from surgical repair.
Jones et al. (1998) conducted a cohort in Large abdominal aortic aneurysms (AAAs) (n=192). AAA diameter ≥6.0 cm vs. AAA diameter 5.0-5.9 cm was evaluated on Rupture within 3 years. In patients unfit for surgery, the 3-year risk of rupture was 41% for AAAs ≥6.0 cm compared to 28% for 5.0-5.9 cm AAAs, though the majority of patients died from other causes.
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