Exogenous progesterone given st 100 or 200 rag/day caused a decrease in concentration of fructose, citric acid, motility, live spermatozoa, and volume of ejaculate in three hulls. Spermatogenesis was disrupted and partially suppressed. Abnormal spermatozoa were increased, with tailless sperm accounting for the major type of abnormality. Semen quality returned to normal after the exogenous hormone was withdrawn. Seminal characteristics from the two low-fertility inbred animals indicated they were secreting abnormally high levels of progesterone.
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Matsuyama et al. (1967) studied this question.
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