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September 17, 2010European Journal of Cardio-Thoracic SurgeryOpen Access

Risk stratification for adult congenital heart surgery

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Key result

Adding an age component to the Comprehensive Aristotle Score improved discrimination for 30-day mortality in adult congenital heart surgery, increasing the c-statistic from 0.66 to 0.76.

Why the study?

Does adding an age component to pediatric risk scores improve mortality risk stratification in adult congenital heart surgery patients?

Population

963 adult patients who underwent congenital cardiac surgery between January 1990 and January 2007 in a…

Comparison

Pediatric congenital cardiac surgery risk scores… vs Original pediatric risk scores without the age…

Design

Cohort

Follow-up

1 year

Authors

MGMenno van GamerenAmphia ZiekenhuisLPLéon M. PutmanLeiden University Medical CenterJTJohanna J.M. TakkenbergCardiac Surgery

Discussion

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Overview

May improve adult congenital heart surgery risk stratification; extends the Comprehensive Aristotle Score but leaves open prospective validation.

Study Design

Type

Cohort (n=963)

Multicenter

No

Structured PICO

Does adding an age component to pediatric risk scores improve mortality risk stratification in adult congenital heart surgery patients?

P
Population
963 adult patients who underwent congenital cardiac surgery at a single center between 1990 and 2007.
E
Exposure
Pediatric congenital cardiac surgery risk scores (RACHS-1, Basic Aristotle Score, STS-EACTS Score, Comprehensive Aristotle Score) combined with an age component
C
Comparator
Original pediatric risk scores without the age component, and age as a sole predictor
O
Outcome
Discrimination (c-statistic) for 30-day mortalityhard clinical

Adding an age component to pediatric risk scores, particularly the Comprehensive Aristotle Score, improves mortality risk stratification in adults undergoing congenital heart surgery.

Cite This Study

Gameren et al. (2010) conducted a cohort in Adult congenital heart surgery (n=963). Pediatric risk scores combined with an age component vs. Original pediatric risk scores was evaluated on 30-day mortality. Adding an age component to the Comprehensive Aristotle Score improved discrimination for 30-day mortality in adult congenital heart surgery, increasing the c-statistic from 0.66 to 0.76.

synapsesocial.com/papers/6a945508fde2ed39e1a0cd0chttps://doi.org/10.1016/j.ejcts.2010.07.032

Topics

Congenital heart disease adults
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Also Consider

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  1. 1Stratification of complexity: The Risk Adjustment for Congenital Heart Surgery-1 Method and The Aristotle Complexity Score – past, present, and future2008 · 55 citations
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  3. 3The RACHS-1 risk categories reflect mortality and length of stay in a Danish population of children operated for congenital heart disease☆2005 · 103 citations
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