Key result
Type II endoleak after EVAR was associated with higher survival (94.1% vs 85.6%, p=.01) and lower freedom from >5mm sac expansion (82.5% vs 93.2%, p=.0001) compared to no endoleak.
Why the study?
Does the development of type II endoleak after EVAR affect mortality and sac expansion in patients undergoing EVAR?
Cohort (n=904)
No
Does the development of type II endoleak after EVAR affect mortality and sac expansion in patients undergoing EVAR?
Absolute Event Rate: 94.1% vs 85.6%
p-value: p=.01
Patients with isolated type II endoleak after EVAR have equivalent aneurysm-related mortality and improved overall survival, supporting conservative management.
Type II endoleak after EVAR was associated with higher survival despite more sac expansion; leaves open optimal management strategies.
OBJECTIVE: Type II endoleak is the most common complication after endovascular abdominal aortic aneurysm repair (EVAR); however, its natural history is unclear. The aim of this study was to examine the incidence and outcomes of type II endoleak, at a single institution after EVAR. METHODS: A total of 904 consecutive patients who underwent EVAR between September 1995 and July 2013 at a single centre were entered onto a prospective database. All patients were followed up by duplex ultrasound (DUSS). Patients who developed type II endoleak were compared for preoperative demographics, mortality, and sac expansion. RESULTS: A total of 175(19%) patients developed type II endoleak over a median follow-up of 3.6 years (1.5-5.9 years); 54% of type II endoleaks spontaneously resolved within 6 months (0.25-1.2 years). No difference was found in preoperative demographics or choice of endograft between the two groups. Survival was significantly higher in the group with type II endoleak (94.1% vs. 85.6%; p = .01) and this effect was most pronounced in those with late type II endoleaks (97.7% vs. 85.6% p = .004). No difference was seen in aneurysm-related mortality or rate of type I endoleak between the two groups. Freedom from sac expansion (>5 mm from preoperative diameter) was significantly lower in the group of patients with type II endoleak (82.5% vs. 93.2%, p = .0001); however, at a threshold of >10 mm from preoperative diameter no difference was seen. CONCLUSIONS: Patients with isolated type II endoleak demonstrate equivalent aneurysm-related mortality and an improved survival.
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Sidloff et al. (2014) conducted a cohort in Abdominal aortic aneurysm post-EVAR (n=904). Type II endoleak vs. No type II endoleak was evaluated on Survival (p=.01). Type II endoleak after EVAR was associated with higher survival (94.1% vs 85.6%, p=.01) and lower freedom from >5mm sac expansion (82.5% vs 93.2%, p=.0001) compared to no endoleak.
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