Key result
Endovascular repair for abdominal aortic aneurysm reduced 30-day mortality versus open repair (1.3% vs 4.7%; OR 0.36) but showed no long-term survival benefit and higher rupture risk.
Why the study?
Does endovascular repair compared to open surgical repair improve early and long-term mortality in patients with abdominal aortic aneurysm?
Meta-Analysis (n=52,220)
Yes
Does endovascular repair compared to open surgical repair improve early and long-term mortality in patients with abdominal aortic aneurysm?
Odds Ratio: 0.36 (95% CI 0.21–0.61)
Absolute Event Rate: 1.3% vs 4.7%
p-value: p=<0.001
EVAR offers an early survival advantage over open repair for AAA, but this benefit is lost over long-term follow-up and is associated with higher risks of reintervention and rupture.
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Supports EVAR for lower perioperative AAA mortality; confirms no long-term survival gain amid higher rupture risk.
Stather et al. (2013) conducted a meta-analysis in abdominal aortic aneurysm (n=52,220). Endovascular repair (EVAR) vs. Open surgical repair was evaluated on 30-day or in-hospital mortality (OR 0.36, 95% CI 0.21-0.61, p=<0.001). Endovascular repair for abdominal aortic aneurysm reduced 30-day mortality versus open repair (1.3% vs 4.7%; OR 0.36) but showed no long-term survival benefit and higher rupture risk.
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