Key result
Endovascular aneurysm repair resulted in similar operative mortality compared to open surgery (0.2% vs. 1.1%, P=0.33) in patients with abdominal aortic aneurysms, with fewer early complications.
Why the study?
Does EVAR compared to open surgery improve survival and reduce complications in patients with abdominal aortic aneurysm?
Observational (n=774)
No
Does EVAR compared to open surgery improve survival and reduce complications in patients with abdominal aortic aneurysm?
Absolute Event Rate: 0.2% vs 1.1%
p-value: p=0.33
EVAR is associated with lower early postoperative complications and shorter hospital stays compared to open surgery, but has lower 5-year survival and reintervention-free rates, likely reflecting the older, higher-risk population selected for EVAR.
EVAR may reduce early complications in AAA repair; leaves open long-term outcomes due to selection bias in observational data.
BACKGROUND: To validate the criteria for endovascular aneurysm repair (EVAR) or open repair of abdominal aortic aneurysm (AAA) at Nagoya University Hospital, the results of both treatments were retrospectively compared. METHODS AND RESULTS: Patient selection for EVAR was primarily based on suitable anatomy, minimum age 75 years, and significant comorbidity. From June 2007 to April 2014, 426 patients were treated via EVAR (EVAR group) and 346 patients were treated with open surgery (OS group). The mortality rates of the EVAR and OS groups were not significantly different (0.2% vs. 1.1%; P=0.33). Patient age, operation time, amount of bleeding, and duration of hospital stay were significantly lower in the EVAR group compared with the OS group. The incidence of comorbidity was higher in the EVAR group compared with the OS group. The incidence of early postoperative complications was significantly higher in the OS group, whereas the incidence of late complications for both groups was similar. The cumulative aneurysm-related survival rates were similar (98.9% vs. 98.5%; P=0.767). The cumulative survival rates and reintervention-free rates at 5 years were lower for the EVAR group (76% vs. 89%, P=0.019; 81% vs. 89%, P=0.046). CONCLUSIONS: Patient selection practices and criteria for EVAR and open repair at Nagoya University Hospital are generally acceptable.
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Yamamoto et al. (2015) conducted an observational in Abdominal aortic aneurysm (n=774). Endovascular aneurysm repair (EVAR) vs. Open surgery (OS) was evaluated on Operative mortality (p=0.33). Endovascular aneurysm repair resulted in similar operative mortality compared to open surgery (0.2% vs. 1.1%, P=0.33) in patients with abdominal aortic aneurysms, with fewer early complications.
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