Key result
Carotid artery stenting was associated with a significantly increased risk of death or stroke at 30 days compared with carotid endarterectomy (OR 1.60; 95% CI 1.26-2.02).
Why the study?
Does carotid artery stenting reduce death or stroke compared to carotid endarterectomy in patients with internal carotid artery stenosis?
Meta-Analysis (n=4,648)
Does carotid artery stenting reduce death or stroke compared to carotid endarterectomy in patients with internal carotid artery stenosis?
Odds Ratio: 1.6 (95% CI 1.26–2.02)
Carotid artery stenting is associated with a higher 30-day risk of death or stroke compared to carotid endarterectomy, though long-term stroke prevention appears equivalent.
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Endarterectomy should be preferred over stenting to minimize 30-day death or stroke; confirms meta-analyses favoring surgery in carotid stenosis.
Roffi et al. (2009) conducted a meta-analysis in internal carotid artery stenosis (n=4,648). Carotid artery stenting (CAS) vs. carotid endarterectomy (CEA) was evaluated on death or stroke at 30 days (OR 1.60, 95% CI 1.26-2.02). Carotid artery stenting was associated with a significantly increased risk of death or stroke at 30 days compared with carotid endarterectomy (OR 1.60; 95% CI 1.26-2.02).
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