Key result
Dynamic capnography is a non-invasive cardiac output monitoring method that has been validated against gold standard reference methods in experimental and clinical settings.
Why the study?
Stable hemodynamics improves pediatric anesthesia outcomes, but most pediatric hemodynamic monitoring methods remain complex and poorly validated.
Dynamic capnography offers a promising, non-invasive approach to continuous hemodynamic monitoring in pediatric anesthesia.
May support non-invasive hemodynamic monitoring in pediatric anesthesia; leaves open prospective validation before clinical adoption.
Recent studies have identified stable hemodynamics as a contributing factor to improve outcome in pediatric anesthesia. So far, most of the hemodynamic monitoring methods applied in children have been complex to apply and often not satisfactory validated. Standard mainstream carbon dioxide analysis in combination with real-time mathematical analysis of the measured capnography data has enabled the development of dynamic capnography, a non-invasively cardiac output monitoring method that can be applied without user practice or need for calibrations. Capnodynamic cardiac output assessment has been extensively validated against gold standard reference methods, both in experimental and clinical settings. This review will describe the principle behind dynamic capnography measurement of cardiac output and mixed venous oxygen saturation. Additionally, the methods limitations and challenges when applied in children will be delineated.
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Karlsson et al. (2021) conducted a review in Pediatric anesthesia. Dynamic capnography (capnodynamics) was evaluated. Dynamic capnography is a non-invasive cardiac output monitoring method that has been validated against gold standard reference methods in experimental and clinical settings.
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