Key result
Noninvasive cardiac output measurement using partial carbon dioxide rebreathing correlated with thermodilution (r=0.83, P<0.03), with a bias of -0.27 L/min and precision of +/-1.49 L/min.
Why the study?
Does noninvasive cardiac output measurement using partial carbon dioxide rebreathing accurately estimate cardiac output compared to thermodilution in children <12 years of age?
Observational (n=37)
Does noninvasive cardiac output measurement using partial carbon dioxide rebreathing accurately estimate cardiac output compared to thermodilution in children <12 years of age?
Effect estimate: r = 0.83
p-value: p=<0.03
Noninvasive cardiac output measurement using partial carbon dioxide rebreathing is clinically acceptable in children with >0.6 m2 body surface area and >300 mL tidal volume.
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May support noninvasive monitoring in select larger children; leaves open prospective validation before routine adoption.
Levy et al. (2004) conducted an observational in Children undergoing cardiac catheterization (n=37). Noninvasive cardiac output measurement using partial carbon dioxide rebreathing vs. Thermodilution cardiac output measurement was evaluated on Correlation, bias, and precision between noninvasive and thermodilution cardiac output measurements (r = 0.83, p=<0.03). Noninvasive cardiac output measurement using partial carbon dioxide rebreathing correlated with thermodilution (r=0.83, P<0.03), with a bias of -0.27 L/min and precision of +/-1.49 L/min.
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