Population
Cells infected with herpes simplex virus
Design
Preclinical
Authors
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No immediate clinical implications; leaves open extension of stepwise viral polyadenylation to other pathogens or models.
The study demonstrates that polyadenylation of viral RNA in herpes simplex virus-infected cells occurs in at least two steps, with distinct poly(A) chain lengths found in nuclear versus cytoplasmic compartments.
Silvertien et al. (1976) studied this question.
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